Publications

 

2021 - Present

97. J. Matragrano, V. W. Cornish, S. Billerbeck. “A Multiplex GPCR-Mediated Peptide Tagging System for a Growing Yeast Synthetic Biology Toolbox.” Helvetica, (2023).

96. T. Crnković, B. Bokor, M. Lockwood, V.W. Cornish. "Peptide Variant Detection by a Living Yeast Biosensor Via an Epitope-Selective Protease." BioDesign Research, 5, Article 0003 (2023).

95.           P. A. Baldera-Aguayo, A. Lee, V. W. Cornish. “High-Titer Production of the Fungal Anhydrotetracycline, TAN-1612, in Engineered Yeasts.” ACS Synth. Biol., 11, 2429–2444 (2022).

94.           S. Billerbeck, V.W. Cornish. “Peptide-Dependent Growth in Yeast Via Fine-Tuned Peptide/GPCR-Activated Essential Gene Expression.” Biochemistry, 61, 150–159 (2022).

93.           M.A. Shandell, Z. Tan, V.W. Cornish. “Genetic Code Expansion: A Brief History and Perspective.” Biochemistry 60, 46, 3455-69 (2021).

92.           E. Herbst, A. Lee, Y. Tang, S.A. Snyder, V.W. Cornish. “Heterologous Catalysis of the Final Steps of Tetracycline Biosynthesis by Saccharomyces cerevisiae.ACS Chem. Bio., 16, 1425-1434 (2021).

91.           A.V. Anzalone, M. Jimenez, V.W. Cornish.  “FRAME-tags: a scalable palette of genetically encoded ratiometric fluorescent barcodes for multiplexed live cell tracking.”  bioRxiv, 04.09.436507 (2021). PDF

90.           J Gerke, D Schneider, A Poehlein, G Braus, V.W. Cornish. “Genome Sequence of Saccharomyces cerevisiae LW2591Y, a Laboratory Strain for In Vivo Multigene Assemblies.” Microbiology Resource Announcements, 10, E01418-20 (2021). HTML | PDF


2016 -2020

89.           M.A. Shandell, J.R. Quejada, M. Yazawa, V.W. Cornish, R.S. Kass.  “Detection of Nav1.5 Conformational Change in Mammalian Cells Using the Noncanonical Amino Acid ANAP.”  Biochemistry117, 1352-1363 (2019). HTML | PDF

88.           A.V. Anzalone, S. Zairis, A.J. Lin, R. Rabadan, V.W. Cornish.  “Interrogation of Eukaryotic Stop Codon Readthrough Signals by In Vitro RNA Selection.”  Biochemistry, 58, 1167-1168  (2019). HTML | PDF

87.           S. Billerbeck, J. Brisbois, N. Agmon, M. Jimenez, J. Temple, M. Shen, J. Boeke, V.W. Cornish. “A Scalable Peptide-GPCR Language for Engineering Multicellular Communication.” Nat. Commun., 9, 5057 (2018). HTMLPDF

86.           R.C. Fleisher, V.W. Cornish, R.L. Gonzalez, Jr.  “D-Amino Acid Mediated Translation Arrest Is Modulated by the Identity of the Incoming Aminoacyl-tRNA.”  Biochemistry, 57, 4241-4246 (2018). HTML | PDF

85.           E. Herbst, P.A. Baldera-Aguayo, H. Lee, V.W. Cornish.  “A Yeast Three Hybrid Assay for Metabolic Engineering of Tetracycline Derivatives.” Biochemistry 57, 4726-4734 (2018). HTML | PDF

84.           V.W. Cornish.  “Ronald Breslow (1931-2017).” Nature, 552, 176 (2017). HTML | PDF

83.           Y.Z. Ng, P.A. Baldera-Aguayo, V.W. Cornish. “Fluorescence Polarization Assay for Small Molecule Screening of FK506 Biosynthesized in 96-Well Microtitre Plates.” Biochemistry, 56, 5260-5268 (2017). HTML | PDF

82.           N. Ostrov†, M. Jimenez†, S. Billerbeck†, J. Brisbois, J. Matragrano, A. Ager, V.W. Cornish. “A Modular Yeast Biosensor for Low-Cost Point-of-Care Pathogen Detection.” Science Advances, 3, e1603221 (2017). HTML | PDF

81.           L. Wei, Z. Chen, L. Shi, R. Long, A.V. Anzalone, L. Zhang, F. Hu, R. Yuste, V.W. Cornish, W. Min. “Super-Multiplex Vibrational Imaging.”  Nature, 544, 465-470 (2017). HTML | PDF

80.           I.V. Sergeyev, R. Rogawski, Y. Li, Ottaviani MF, V.W. Cornish, A.E. McDermott. “ Dynamic Nuclear Polarization Signal Enhancement with High-Affinity Biradical Tags.” J. Phys. Chem. B121, 1169-1175 (2017). HTML | PDF

79.           A.V. Anzalone, Z. Chen, V.W. Cornish. “Synthesis of Photoactivatable Azido-Acyl Caged Oxazine Fluorophores for Live-Cell Imaging.” Chem. Commun., 52, 9442-9445 (2016). HTML | PDF

78.           J.D. Boeke, G. Church, A. Hessel, N.J. Kelley, et al. (V.W. Cornish).  “GENOME ENGINEERING.  The Genome Project-Write.” Science, 353, 126-127 (2016). HTML | PDF

77.           X. Hu, C. Jing, X. Xu, N. Nakazawa, V.W. Cornish, F.M. Margadant, M.P. Sheetz. “Cooperative Vinculin Binding to Talin Mapped by Time-Resolved Super Resolution Microscopy.” Nano Lett., 16, 4062-4068 (2016). HTML | PDF

76.           A.V. Anzalone*, A.J. Lin, S. Zairis, R. Rabadan, V.W. Cornish*. “Reprogramming Eukaryotic Translation with Ligand-Responsive Synthetic RNA Switches.” Nature Methods, 13, 453-458 (2016). HTML | PDF


2010 -2015

75.           M.T. Englander, J.L. Avins, R.C. Fleisher, B. Liu, P.R. Effraim, J. Wang, K. Schulten, T.S. Leyh, R.L. Gonzalez Jr.*, V.W. Cornish*. “The Ribosome Can Discriminate the Chirality of Amino Acids Within Its Peptidyl Transferase Center.” Proc. Natl. Acad. Sci. USA, 112, 6038-6039 (2015). HTML | PDF

74.           W.S. Yang, R. SriRamaratnam, M.E. Welsch, K. Shimada, R. Skouta, V.W. Viswanathan, J.H. Cheah, P.A. Clemons, A.F. Shamji, C.B. Clish, L.M. Brown, A.W. Girotti, V.W. Cornish, S.L. Schreiber, B.R. Stockwell. “Regulation of Ferroptotic Cancer Cell Death by GPX4.” Cell, 156, 317-331 (2014). HTML | PDF

73.           T.Y. Wang, L.J. Friedman, J. Gelles, W. Min, A.A. Hoskins, V.W. Cornish. “The Covalent Trimethoprim Chemical Tag Facilitates Single Molecule Imaging with Organic Fluorophores.” Biophys. J., 106, 272-278 (2014). HTML | PDF

72.        M.D. Harton, L.M. Wingler, V.W. Cornish. “Transcriptional Regulation Improves the Throughput of Three-Hybrid Counter Selections in Saccharomyces cerevisiae.” Biotechnol. J., 8, 1485-1491 (2013). HTML | PDF

71.        C. Jing, V.W. Cornish. “Design, Synthesis and Application of the Trimethoprim Based Chemical Tag for Live-Cell Imaging.” Curr. Protoc. Chem. Biol., 5, 131-155 (2013). HTML | PDF

70.           Z. Chen, V.W. Cornish, W. Min. “Chemical Tags: Inspiration for Advanced Imaging Techniques.” Curr. Opin. Chem. Biol., 17, 637-643 (2013). HTML | PDF

69.           C. Jing, V.W. Cornish. “A Fluorogenic TMP-tag for High Signal-to-Background Intracellular Live Cell Imaging.” ACS Chem. Biol., 8, 1704-1712 (2013). HTML | PDF

68.           N. Ostrov, L.M. Wingler, V.W. Cornish. “Gene Assembly and Combinatorial Libraries in S. cerevisiae via Reiterative Recombination.” Methods Mol. Biol., 978, 187-203 (2013). HTML | PDF

67.           A.R. Shepard, R.E. Conrow, M. Rezwan, K. Rutschmann, I.-H. Pang, D. Auerbach, R.P. SriRamaratnam, V.W. Cornish. “Identification of PDE6D as a Molecular Target of Anecortave Acetate Via Methotrexate-Anchored Yeast Three-Hybrid Screen.” ACS Chem. Biol., 8, 549-558 (2013). HTML | PDF

66.           A. Anzalone, Z. Chen, T. Wang, V.W. Cornish. “A Common Diaryl Ether Intermediate for the Gram-Scale Synthesis of Oxazine and Xanthene Fluorophores.” Angew. Chem., 52, 650-654 (2013). HTML | PDF

65.          D.W. Romanini, P. Peralta-Yahya, V. Mondol, V.W. Cornish. “A Heritable Recombination System for Synthetic Darwinian Evolution in Living Cells.” ACS Synth. Biol., 1, 602-609 (2012). Featured in Chem. & Eng. News, 90, 10 (2012). HTML | PDF

64.          Ruble JF, Lefurgy ST, V.W. Cornish, Powers RA. “Structural Analysis of the Asn152Gly Mutant of P99 Cephalosporinase.” Acta Crystallogr D Biol Crystallogr., 68, 1189-1193 (2012). HTML | PDF

63.          Z. Chen, C. Jing C, S.S. Gallagher, M.P. Sheetz, V.W. Cornish.  “Second-Generation Covalent TMP-Tag for Live Cell Imaging.”  J. Am. Chem. Soc., 134, 13692-13699 (2012). HTML | PDF

62.          E. Gatzogiannis, Z. Chen, L. Wei, R. Wombacher, Y.T. Kao, G. Yefremov, V.W. Cornish, W. Min. “ Mapping Protein-Specific Micro-Environments in Live Cells by Fluorescence Lifetime Imaging of a Hybrid Genetic-Chemical Molecular Rotor Tag.” Chem. Commun., 48, 8694-8696 (2012). HTML | PDF

61.          D.W. Romanini, V.W. Cornish. “Protein Labeling: Playing Tag with Proteins.” Nat. Chem., 4, 248-250 (2012)(Invited Commentary). HTML | PDF

60.          C. Jing, V.W. Cornish. “Chemical Tags for Labeling Proteins Inside Living Cells.” Acc. Chem. Res., 44, 784-792 (2011). (Invited Review). HTML | PDF

59.          L.M. Wingler*, V.W. Cornish*. “Reiterative Recombination for the In Vivo Assembly of Libraries of Multi-Gene Pathways.” Proc. Natl. Acad. Sci. USA, 4, 391-402 (2011). HTML | PDF

58.          R. Wombacher V.W. Cornish. “Chemical Tags: Applications in Live Cell Fluorescence Imaging.” J. Biophotonics, 4, 391-402 (2011). (Invited Review). HTML | PDF

57.          A.A. Hoskins, L.J. Friedman, S.S. Gallagher, D.J. Crawford, E.G. Anderson, R. Wombacher, N. Ramirez, V.W. Cornish, J. Gelles*, M.J. Moore*. “Ordered and Dynamic Assembly of Single Spliceosomes.” Science, 331, 1289-1295 (2011). HTML | PDF

56.          L.M. Wingler, V.W. Cornish. “A Library Approach for the Discovery of Customized Yeast Three-Hybrid Counter Selections.” ChemBioChem, 12, 715-717 (2011). HTML | PDF

55.          N. Pirakitikulr*, N. Ostrov*, P. Peralta-Yahya, V.W. Cornish. “PCRless Library Mutagenesis via Oligonucleotide Recombination in Yeast.” Protein Science, 19, 2336-2346 (2010). HTML | PDF

54.          R. Wombacher, M. Heidbreder, S. van de Linde, M.P. Sheetz, M. Heilemann*, V.W. Cornish*, M. Sauer*. “Live Cell Super-Resolution Imaging with Trimethoprim Conjugates.” Nature Methods, 7, 717-719 (2010). HTML | PDF

53.         S.S. Gallagher, C. Jing, D.S. Peterka, M. Konate, R. Wombacher, L.J. Kaufman, R. Yuste, V.W. Cornish. “A Trimethoprim-Based Chemical Tag for Live Cell Two-Photon Imaging.” ChemBioChem, 11, 782-784 (2010). HTML | PDF

52.         Y. Cai, O. Rossier, N.C. Gauthier, N. Biais, M.A. Fardin, X. Zhang, L.W. Miller, B. Ladoux, V.W. Cornish, M.P. Sheetz. “Cytoskeletal Coherence Requires Myosin-IIA Contractility.” J. Cell Sci., 123, 413-423 (2010). HTML | PDF


2005 -2009

51.         P.R. Effraim, J. Wang, M.T. Englander, J. Avins, T.S. Leyh*, R.L. Gonzalez*, Jr., V.W. Cornish*. “Natural Amino Acids Do Not Require Their Native tRNAs for Efficient Selection by the Ribosome.” Nature Chem. Biol., 5, 947-953 (2009). HTML | PDF

50.        M. Pavlov, R. Watts, Z. Tan, V.W. Cornish, M. Ehrenberg, A. Forster. "Slow Peptide Bond Formation by Proline and Other N-alkylamino Acids in Translation." Proc. Natl. Acad. Sci., 106, 50-54 (2009). HTML | PDF

49.        S.S. Gallagher, J.E. Sable, M.P. Sheetz, V.W. Cornish. "An In Vivo Covalent TMP-Tag Based on Proximity-Induced Reactivity.” ACS Chem. Biol., 4, 547-556 (2009). HTML | PDF

48.        V.W. Cornish, S.S. Gallagher. “Fluorescence in Living Systems: Applications in Chemical Biology.” In Wiley Encyclopedia of Chemical Biology, T.P. Begley, Editor. 2009, John Wiley & Sons, Inc.: Hoboken. pp. 28-38 (2009). HTML | PDF

47.        P. Peralta-Yahya, B. T. Carter, H. Lin, H. Tao. V.W. Cornish. “A High-Throughput Selection for Cellulase Catalysts Using Chemical Complementation.” J. Am. Chem. Soc., 130, 17446-17452 (2008). HTML | PDF

46.        J.L. Czlapinski, M.W. Schelle, L.W. Miller, S.T. Laughlin, J.J. Kohler, V.W. Cornish, C.R. Bertozzi. “Conditional Glycosylation in Eukaryotic Cells Using a Biocompatible Chemical Inducer of Dimerization.” J. Am. Chem. Soc., 130, 13186-13187 (2008). HTML | PDF

45.       H. Tao, P. Peralta-Yahya, J. Decatur, V.W. Cornish. "Characterization of a New Glycosynthase Cloned by Using Chemical Complementation." ChemBioChem, 9, 681-684 (2008). HTML | PDF

44.       J.E. Bronson, W.W. Mazur, V.W. Cornish. "Transcription Factor Logic Using Chemical Complementation." Molecular BioSystems, 4, 56 (2008). HTML | PDF

43.       S.T. Lefurgy, R.M. de Jong, V.W. Cornish. "Saturation Mutagenesis of Asn152 Reveals a Substrate Selectivity Switch in P99 Cephalosporinase." Protein Science, 16, 2636-2646 (2007). HTML | PDF

42.       B. Zhang, Z. Tan, L.G. Dickson, M.N.L. Nalam, V.W. Cornish, A. Forster.  "Specificity of Translation for N-Alkyl Amino Acids." J. Am. Chem. Soc., 129, 11316-11317 (2007). HTML | PDF

41.       N.T. Calloway, M. Choob, A. Sanz, M.P. Sheetz, L.W. Miller, V.W. Cornish. "Optimized Fluorescent Trimethoprim Derivatives for In Vivo Protein Labeling." ChemBioChem., 8, 767-774 (2007). HTML | PDF

40.      S. Gallagher, L.W. Miller, V.W. Cornish. "An Orthogonal Dexamethasone-Trimethoprim Yeast Three-Hybrid System." Anal. Biochem., 363, 160-162 (2006). HTML | PDF

39.       H. Tao, P. Peralta-Yahya, H. Lin, V.W. Cornish. "Optimized Design and Synthesis of Chemical Dimerizer Substrates for Detection of Glycosynthase Activity via Chemical Complementation." Bioorg. Med. Chem., 14, 6940-6953 (2006). HTML | PDF

38.       P. Peralta-Yahya, V.W. Cornish. "Bringing the Power of Genetics to Chemistry."  In Chemical Biology, S.L. Schreiber, T. Kapoor, G. Weiss, Eds. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, vol. 1, pp. 199-226 (2006). (Invited Review). HTML | PDF

37.       V.W. Cornish. “Biological Chemistry: Catalytic Competition for Cells.” Nature, 440, 156-157 (2006). (Invited News and Views). HTML | PDF

36.       S. Lefurgy, V.W. Cornish. "Chemical Complementation." In Enzyme Assays: High-throughput Screening, Genetic Selection and Fingerprinting, J-L. Reymond, Ed. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, pp. 183-219 (2005). (Invited Review). HTML

35.       Z. Tan, S.C. Blacklow, V.W. Cornish, A.C. Forster. “De Novo Genetic Codes and Pure Translation Display.” Methods, 36, 279-90 (2005). HTML | PDF

34.      B.T. Carter, H. Lin, S.D. Goldberg, E.A. Althoff, J. Raushel, V.W. Cornish. "Investigation of the Mechanism of Resistance to Third-Generation Cephalosporins by Class C b-Lactamases Using Chemical Complementation." ChemBioChem, 6, 2055-2067 (2005). HTML | PDF

33.     L. Miller, Y. Cai, M. Sheetz, V.W. Cornish. "In Vivo Labeling with Trimethoprim Conjugates: A Flexible Chemical Tag." Nature Methods, 2, 255-257 (2005). HTML | PDF

32.     L. Miller, V.W. Cornish. "Selective Chemical Labeling of Proteins in Living Cells." Curr. Opin. Chem. Biol., 9, 1-6 (2005). (Invited Review). HTML | PDF


2000 -2004

31.     H. Lin, H. Tao, V.W. Cornish. "Directed Evolution of a Glycosynthase Via Chemical Complementation." J. Am. Chem. Soc., 126, 15051-15059 (2004). Featured in Chem. & Eng. News, 82:46, 32 (2004). HTML | PDF

30.     Z. Tan, A. Forster, S. Blacklow, V.W. Cornish. "Amino Acid Backbone Specificity of the E. coli Translation Machinery." J. Am. Chem. Soc., 126, 12752-12753 (2004). HTML | PDF

29.     A.C. Forster, V.W. Cornish, S.C. Blacklow. "Pure Translation Display." Anal. Biochem., 333, 358-364 (2004). HTML | PDF

28.     K. Suwwan deFelipe, E.A. Althoff, B.T. Carter, V.W. Cornish. "Correlation Between Ligand-Receptor Affinity and the Transcription Readout in a Yeast Three-Hybrid System."  Biochemistry, 43, 10353-10363 (2004). HTML | PDF

27.     S. Lefurgy, V.W. Cornish. "Finding Cinderella After the Ball: a Three-Hybrid Approach to Drug Target Identification." Chem. Biol., 11, 151-153 (2004)(Invited Commentary). HTML | PDF

26.     D. Sengupta, H. Lin, S. Goldberg, J. Mahal, V.W. Cornish. "Correlation Between Catalytic Efficiency and the Transcription Read-Out in Chemical Complementation, a High-Throughput Assay for Enzyme Catalysis." Biochemistry, 43, 3570-3581 (2004). HTML | PDF

25.     B.F. Gherman, S.D. Goldberg, V.W. Cornish, R.A. Friesner. "Mixed Quantum Mechanical/Molecular Mechanical (QM/MM) Study of the Deacylation Reaction in a Penicillin Binding Protein (PBP) Versus in a Class C b-Lactamase." J. Am. Chem. Soc., 126, 7652-7664 (2004). HTML | PDF

24.     L. Miller, J. Sable, P. Goelet, M. Sheetz, V.W. Cornish. "Methotrexate Conjugates: A Molecular In Vivo Protein Tag." Angew. Chem., 116, 1704-1707 (2004); Angew. Chem. Int. Ed., 43, 1672-1675 (2004). HTML | PDF

23.     S. Goldberg, W. Iannuccilli, T. Nguyen, J. Ju, V.W. Cornish. "Identification of Residues Critical for Catalysis in a Class C b-Lactamase by Combinatorial Scanning Mutagenesis." Protein Science, 12, 1633-1645 (2003). HTML | PDF

22.     A. Forster, Z. Tan, M.N.L. Nalam, H. Lin, H. Qu, V.W. Cornish, S. Blacklow. "Programming Peptidomimetic Syntheses by Translating Genetic Codes Designed De Novo." Proc. Natl. Acad. Sci. USA, 100, 6353-6357 (2003). Featured in Chem. Biol., 10, 586-587 (2003) and in Chem. & Eng. News, 82, 64-68 (2004). HTML | PDF

21.     K. Baker, D. Sengupta, G. Salazar-Jimenez, V.W. Cornish. "An Optimized Dexamethasone-Methotrexate Yeast 3-Hybrid System for High-Throughput Screening of Small Molecule-Protein Interactions." Anal. Biochem., 315, 134-137 (2003). HTML | PDF

20.     K. Baker, C. Bleczinski, H. Lin, G. Salazar-Jimenez, D. Sengupta, S. Krane, V.W. Cornish. "Chemical Complementation: A Reaction-Independent, High-Throughput Genetic Assay for Enzyme Catalysis." Proc. Natl. Acad. Sci. USA, 99, 16537-16542 (2002). Featured in a commentary in Proc. Natl. Acad. Sci. USA, 99, 16513-16515 (2002) and in Chem. & Eng. News, 81, 24 (2003). HTML | PDF

19.     H. Tao, V.W. Cornish. "Milestones in Directed Enzyme Evolution." Curr. Opin. Chem. & Biol., 6, 858-864 (2002).(Invited Review). HTML | PDF

18.     H. Lin, V.W. Cornish. "Screening and Selection Methods for the Large Scale Analysis of Protein Function." Angew. Chem., 114, 4580-4606 (2002); Angew. Chem. Int. Ed., 41, 4402-4425 (2002). (Invited Review). HTML | PDF

17.     W. Abida, B. Carter, E. Althoff, H. Lin, V.W. Cornish. “Receptor-Dependence of the Transcription Read-Out in a Small-Molecule Three-Hybrid System.” ChemBioChem, 3, 887-895 (2002). HTML | PDF

16.     E.A. Althoff, V.W. Cornish. "A Bacterial Small-Molecule Three-Hybrid System." Angew. Chem.114, 2433-2436 (2002); Angew. Chem. Int. Ed., 41, 2327-2330 (2002). HTML | PDF

15.     B.T. Carter, H. Lin, V.W. Cornish. "Yeast n-Hybrid Systems for Molecular Evolution." In Directed Molecular Evolution of Proteins, S. Brakmann, K. Johnsson, Eds. Wiley-VCH Verlag, Weinheim, 2002. (Invited Review).

14.     B.T. Carter, V.W. Cornish.  Book Review: Two-Hybrid Systems Methods and Protocols. Edited by Paul N. MacDonald. ChemBioChem3, 476-477 (2002). (Invited Review).

13.     V.W. Cornish. "Probing Enzyme Complexity." Chem. & Eng. News, 79, 64 (2001). Young Investigator Featured in 125th Year Anniversary Issue. (Invited Review). PDF

12.     H. Lin, V.W. Cornish. “In Vivo Protein-Protein Interaction Assays: Beyond Proteins.” Angew. Chem., 114, 895-899 (2001); Ang. Chem. Int. Ed.40, 871-875 (2001). (Invited Review). HTML | PDF

11.     H. Lin, W. Abida, R.T. Sauer, V.W. Cornish. “Dexamethasone-Methotrexate:  An Efficient Chemical Inducer of Protein Dimerization In Vivo.” J. Am. Chem. Soc.122, 4247-4248 (2000). Featured in Chem. & Eng. News78, 52 (2000). HTML | PDF


1993 -1999

10.      Y. Webb, X. Zhou, L. Ngo, V.W. Cornish, J. Stahl, H. Erdjument-Bromage, P. Tempst, R. Rifkind, P. Marks, R. Breslow and V. Richon. "Photoaffinity Labeling and Mass Spectrometry Identify Ribosomal Protein S3 as a Potential Target for Hybrid Polar Cytodifferentiation Agents." J. Biol. Chem., 274, 14280-14287 (1999). HTML | PDF

9.       J.S. Thorson, V.W. Cornish, J.E. Barrett, S.T. Cload, T. Yano, P.G. Schultz. "Insertion of Unnatural Amino Acids Using Chemical Acylation Techniques." Methods in Molecular Biology: Protein Synthesis: Methods and Protocols77, 43-73 (1998). (Methods).

8.       J.T. Koh, V.W. Cornish, P.G. Schultz. "An Experimental Approach to Evaluating the Role of Backbone Interactions in Proteins Using Unnatural Amino Acid Mutagenesis." Biochemistry36, 11314-11322 (1997). HTML | PDF

7.       V.W. Cornish, K.M. Hahn, P.G. Schultz. "Site-Specific Protein Modification Using a Ketone Handle." J. Am. Chem. Soc.,118, 8150-8151 (1996). HTML | PDF

6.       V.W. Cornish, D. Mendel, P.G. Schultz. "Probing Protein Structure and Function with an Expanded Genetic Code." Angew. Chem. Int. Ed. Engl., 34, 621-633 (1995). (Invited Review). HTML | PDF

5.       D. Mendel, V.W. Cornish, P.G. Schultz.  "Site-Directed Mutagenesis with an Expanded Genetic Code." Ann. Rev. Biophys. Biomol. Struct.24, 435-462 (1995). (Invited Review). HTML | PDF

4.       V.W. Cornish, M.I. Kaplan, D.L. Veenstra, P.A. Kollman, P.G. Schultz. "Stabilizing and Destabilizing Effects of Placing b-Branched Amino Acids in Protein a-Helices." Biochemistry33, 12022-12031 (1994). HTML | PDF

3.       V.W. Cornish, P.G. Schultz. "A New Tool for Studying Protein Structure and Function." Curr. Opin. Struct. Biol.,4, 601-607 (1994). (Invited Review). HTML | PDF

2.       V.W. Cornish, D.R. Benson, C.A. Altenbach, K. Hideg, W.L. Hubbel, P.G. Schultz. "Site-Specific Incorporation of Biophysical Probes into Proteins." Proc. Natl. Acad. Sci. USA91, 2910-2914 (1994). HTML | PDF

1.       H.H. Chung, D.R. Benson, V.W. Cornish, P.G. Schultz. "Probing the Role of Loop 2 in Ras Function with Unnatural Amino Acids." Proc. Natl. Acad. Sci. USA90, 10145-10149 (1993). HTML | PDF